The role of glycosylated metabolic products in the formation of vascular complications of diabetes

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Abstract


Primary glycosylation undergoes not only albumin, but also other plasma proteins. Glycosylation of apolipoproteins, which are part of low density lipoproteins (LDL), leads to an increase in electrophoretic mobility and a slowdown in the degradation of the latter using fibroblasts, which can contribute to the development of atherosclerosis [51]. Glycosylated LDL are actively subjected to secondary oxidation, as a result of which they acquire atherogenic properties [32].

Significant changes were found in the exchange of very low density glycosylated lipoproteins [35]. The triglycerides contained in them are less likely to be cleaved by lipoprotein lipase. This is one of the factors in maintaining hypertriglyceridemia in diabetes.


N. I. Verbovaya

Samara State Medical University

Author for correspondence.
Email: probl@endojournals.ru

Russian Federation, Samara

E. A. Lebedeva

Samara State Medical University

Email: probl@endojournals.ru

Russian Federation, Samara

  1. Викторова Л. Н., Наводный О. А., Городецкий В. К. // Лаб. дело. - 1990. - № 7. - С. 14-16.
  2. Денисенко Т. В. // Вопр. мед. химии. — 1990. — № 2. — С. 5-10.
  3. Лукьянчиков В. С. И Кардиология. — 1991. — № 11. — С. 88-94.
  4. Свистунова О. И., Титов В. Н. // Клин. лаб. диагн. — 1990- № 11-12. - С. 22-30.
  5. Arbuster D. А. // Clin. Chem. - 1987. - Vol. 33, N 12 - Р. 2153-2163.
  6. Brownlee M.f Vlassara H., Cerami A. // Diabetes. — 1985. — Vol. 34, N 9. - P. 938-941.
  7. Brownlee M. // Science. - 1986. - Vol. 232, N 27. - P. 1629-1631.
  8. Brownlee M., Cerami A., Vlassara //. // N. Engl. J. Med. — 1988. - Vol. 318, N 20. - P. 1315-1321.
  9. Bucala R., Tracey K. J., Cerami A. // J. clin. Invest. — 1991. Vol. 87, N 2. - P. 432-438.
  10. Bucala R., Makita Z., Koschinsky T. // J. Amer. Diabet. Assoc. 1993. - Vol. 42, Suppl. 1. - P. 119A.
  11. Bunn H. F. U Diabetes. - 1981. - Vol. 30, N 7. - P. 613— 617.
  12. Cameron N. E., Cotter M. A. // Diabet. Med. — 1993. — Vol. 10, N 7. - P. 598-599.
  13. Cameron N. E., Cotter M. A. // Diabet. Metab. Rev. — 1994. Vol. 10, N 3. - P. 189-224.
  14. Cerami A., Vlassara H., Brownlee M. // Metabolism. — 1985. Vol. 34. - P. 37-44.
  15. Ceriello A., Giugliano D., Dello Russo P., Torella R. // Diabet. Metab. - 1988. - Vol. 14, N 1. - P. 40-42.
  16. Ceriello A., Quatraro A., Caretta F. et al. // Ibid. — 1990. — Vol. 16, N 4. - P. 318-322.
  17. Ceriello A., Quatraro A., Caretta F. et al. // Diabet. Metab. — 1990- Vol. 6, N 4. - P. 318-322.
  18. Ceriello A., Giugliano D., Quatraro A. et al. // Diabet. Care. — 1990- Vol. 14, N 1. - P. 68-72.
  19. Cohen M. P., Urganivia E., Surma M., Wu V. Y. // Biochem. biophys. Res. Commun. — 1980. — Vol. 95. — P. 765—769.
  20. Compagnucci P., Cortechini M. G., Bolli G. et al. // Diabetes. 1981. - Vol. 30, N 7. - P. 607-612.
  21. Corbett J. A., McDaniel M. L. // Ibid. — 1992. — Vol. 41, N 8. - P. 897-903.
  22. Corbett J. A., Tilton R. J., Chang K. et al. // Ibid. - N 4. - P. 552-556.
  23. Corbett J. A., Kwon G., Miskot T. et al. // J. Amer. Diabet. Assoc. - 1993. - Vol. 42, Suppl. 1. - P. 149A.
  24. Day J. E, Thorpe S. R., Baynes J. W. // J. biol. Chem. — 1979. - Vol. 254. - P. 595-597.
  25. Gilcrease M., Hooven P. L. // Diabetologia. — 1990. — Vol. 33, N 6. - P. 329-333.
  26. Gillery P., Monboisse J. C., Maquart F. X., Borel J. P. // Diabet. Metab. - 1988. - Vol. 14. - P. 25-30.
  27. Guthrow С. E., Morris M. A., Day J. F. et al. // Proc. natl. Acad. Sci. USA. - 1979. - Vol. 76. - P. 4258-4261.
  28. Hamines H. P., Uhlmann M., Weis A., Federlin K. // European Association for the Study of Diabetes. Annual Meeting, 29-th. Abstracts.
  29. Hanssen K. F, Bangstad H. J., Brinchmann-Hansen O., Dahl- Jordasen K. // Diabet. Med. — 1992. — Vol. 9, N 8. — P. 697-705.
  30. HuiJberts M. S. P., Wolttehuttl В. H. R., Crijns F. R. J. // J. Amer. Diabet. Assoc. — 1993. — Vol. 42, Suppl. 1. — P. 96A.
  31. Hunt J. V, Dean R. T., Wolff S. P. // Biochem. J. - 1988. - Vol. 256, N 1. - P. 205-212.
  32. Kobayashi K., Makasado M., Watanable J. et al. // J. Amer. Diabet. Assoc. - 1993. - Vol. 42, Suppl. 1. - P. 235A.
  33. Makita Z., Fun H., Vlassara H. // Ibid. — P. 8A.
  34. Makita Z, Fun H., Laggare H. V Ц Ibid. - P. 192.
  35. Mamo J. C. L., Szeto L., Steiner G. // Diabetologia. — 1990. - Vol. 33, N 6. - P. 339-345.
  36. Monnier V. M., Vishwanath V., Frank К. E. et al. // N. Engl. J. Med. - 1986. - Vol. 314. - P. 403-408.
  37. 'Monnier V. M., Hayase E, Njoroge F. G. et al. // Diabet. Metab. - 1990. - Vol. 16, N 4. - P. 367-368.
  38. Odetti P. R., Borgoglio A., Pascale A. et al. // Diabetes. — 1988 - Vol. 139, N 7. - P. 796-802.
  39. Radoff S., Makita Z., Vlassara H. // Ibid. — 1991. — Vol. 40, N 12. - P. 1731-1738.
  40. Robins S. P., Bailay A. J. // Biochem. biophys. Res. Commun. 1972. - Vol. 48. - P. 76-84.
  41. Schnider S. L., Kohn R. R. // J. clin. Invest. — 1980. — Vol. 66. - P. 1179-1181.
  42. Stevens M., Dananberg J., Lattimer S. et al. // J. Amer. Diabet. Assoc. — 1993. — Vol. 42, Suppl. 1. — P. 149A.
  43. Stolba P., Hatle K., Krnakova A. et al. // Diabetologia. — 1984 - Vol. 30. - P. 529A.
  44. Stolba P., Streda M., Vordra K. et al. // Ibid. — 1988. — Vol. 31, N 7. - P. 546A.
  45. Tarsio J. F., Reger L. A., Furcht L. T. // Diabetes. — 1988. — Vol. 37, N 5. - P. 532-539.
  46. Vlassara H, Brownlee M., Cerami A. // J. exp. Med. — 1984. Vol. 60, N 1. - P. 197-207.
  47. Vlassara H., Brownlee M., Cerami A. // Diabetes. — 1989. — Vol. 37, N 4. - P. 456-461.
  48. Vlassara H. // Diabet. Care. — 1990. — Vol. 13, N 11. — Suppl. 4. - P. 1180-1185.
  49. Wales J. К. H., Forrest A. R. W. // Diabet. Med. — 1993. — Vol. 10, N 6. - P. 564—567.
  50. Williamson J. R., Chang K., Ido Y. et al. // Diabet. Metab. — 1988 - Vol. 16, N 4. - P. 369-370.
  51. Witztum J. L., Mahoney E. M., Franks M. J. et al. // Diabetes. 1982. - Vol. 31, N 4. - P. 283-291.
  52. Yamanouchi T., Akanuma Y., Toyota T. et al. // Ibid. — 1991. Vol. 40, N 1. - P. 52-57.

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Copyright (c) 1997 Verbovaya N.I., Lebedeva E.A.

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