Adrenocortical and testicular hormones during emotional stress in rats genetically predisposed to cataleptic reaction

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Abstract


GC rats bred from Wistar stock for genetic predisposition to cataleptic reaction are characterized by a slightly lower blood testosterone level than the control Wistar rats. This difference becomes significant after immobilization stress when the level of testosterone increases by 14% in GC and by 61% in Wistar rats (p<0.05). Stress brought about a 68% increase in DOC production by the adrenal tissue in Wistar but caused no changes in GS animals. Stress-induced decrease in aldosterone production was greater in GC and resulted in a significant difference between the two strains (0.77 ± 0.09 and 0.46 ± 0.06 mg/100 mg tissue, p<0.05). The detected endocrine characteristics of GC rats resemble the picture of chronic stress and are similar to those known about male schizophrenics.


K. A. Shulga

Institute of Cytology and Genetics SB RAS

Author for correspondence.
Email: probl@endojournals.ru

Russian Federation, Novosibirsk

T. A. Alekhina

Institute of Cytology and Genetics SB RAS

Email: probl@endojournals.ru

Russian Federation, Novosibirsk

V. G. Kolpakov

Institute of Cytology and Genetics SB RAS

Email: probl@endojournals.ru

Russian Federation, Novosibirsk

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Copyright (c) 1997 Shulga K.A., Alekhina T.A., Kolpakov V.G.

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